What is necrosis?

Tamara Sidorova
Tamara Sidorova
March 25, 2013

It is no secret that many diseases and some injuries can lead to such a serious ailment as necrosis. “What is necrosis?” You ask. Read below.

Necrosis, derived from the Greek word "νεκρός", which translates as dead. Also, this disease is called mortification (mortification) - killing, gangrene. The medical directory says: "Necrosis is the partial or complete die-off of the cells of an organ or tissue that occurs as a result of various diseases, injuries or a sudden impairment of blood circulation." What are the causes of necrosis?

Factors leading to necrosis

The factors affecting the development of this terrible disease are many, but the following main causes of necrosis are distinguished:

  1. Mechanical damage. Injuries resulting in rupture or crush of organs or tissues.
  2. Thermal, chemical or electrical damage. All types of burns, regardless of the reasons for their production (current, chemical elements, thermal) and frostbite.
  3. Microbial toxins (gas gangrene of the extremities, gangrenous appendicitis), external infection.
  4. Infectious and non-communicable diseases (diabetes, typhoid fever, syphilis).
  5. Circulatory disorders. This disease occurs in bedridden and debilitated patients (bedsores) and with a long absence of a rush of blood (clamped to the leg, the tourniquet was tightly put tight).

There are four stages of necrosis.

  • The first is paranecroses, reversible changes.
  • The second is necrobiosis, irreversible dystrophic changes.
  • The third is autolysis, decomposition of dead substrate.
  • The fourth - the complete death of cells, there is nothing to save.

I would like to note that most often this disease affects the tissues of the most important organs: heart (heart attack), brain, lungs. Now you know what tissue necrosis is. This is their death, and it will be slow or fast, depending on many factors. But it is better to lead a healthy lifestyle and to get acquainted with diseases only out of curiosity and in absentia.

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